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On June 7th, AstraZeneca CEO Robert Soriot warned that, given the terms of its agreement with the Trump administration to reduce drug costs for US patients, the pharmaceutical giant may be forced to suspend the launch of new drugs in the UK and Europe if it cannot secure higher drug prices. Soriot stated that European countries must increase investment in innovative drugs, otherwise the Anglo-Swiss joint venture will have no choice but to focus almost entirely on the US market, as nearly half of its revenue comes from the US.On June 7th, Eli Lilly (LLY.N) announced the results of a trial of its next-generation weight-loss drug, Retatrutide, to medical experts. The results showed that in addition to promoting weight loss and relieving knee pain, the drug can also reduce the severity of sleep apnea. In a phase 3 clinical trial, Eli Lilly found that once-weekly injections of Retatrutide reduced symptoms of moderate to severe obstructive sleep apnea by 60.6% in obese adult patients. In the same trial, Eli Lilly also found that the drug reduced pain in patients with knee osteoarthritis by up to 73.1%.On June 7th, the Nansha District Government and Baoan District Government of Guangzhou signed a strategic cooperation framework agreement. The two districts will promote comprehensive cooperation in multiple areas, including industrial collaboration, technological innovation, talent exchange, infrastructure, and a high-quality living environment, jointly creating a new model of coordinated development in the Greater Bay Area and supporting the high-quality development of the "Golden Inner Bay." In the area of peoples livelihood, the two districts will pilot projects in areas such as sharing high-quality educational resources, cross-regional medical cooperation, mutual recognition and interoperability of social security rights, and cross-regional use of housing provident funds.On June 7th, German Chancellor Merz stated at the CDU state party congress in Mecklenburg-Western Pomerania that despite disagreements within the ruling coalition on some issues, the coalition still possesses the ability to "push forward reforms and maintain unity and cooperation." He believes that the current difficulties can be overcome, and Germany is expected to show a new development trend in a relatively short period of time. When discussing key reform areas, Merz mentioned digitalization, streamlining administrative procedures, improving infrastructure, and ensuring energy supply. He stated that Germany has the potential to build a more efficient railway transport system, enhance data transmission capabilities, and maintain international competitiveness in modern climate protection technologies. Furthermore, Germany also has the capability to build one of the most powerful conventional armed forces in Europe.On June 7th, it was learned from the Hainan Provincial Housing Provident Fund Management Bureau that, in order to standardize the management of individual housing provident fund accounts and improve data quality, the bureau will conduct a cleanup of "one person, multiple accounts" among contributors. According to reports, during a special investigation, the bureau discovered that some contributors had "one person, multiple accounts" (multiple accounts under different names using the same ID number). According to the "Housing Provident Fund Management Regulations," each employee can only have one housing provident fund account. The bureau has issued a notice reminding relevant contributing units and contributors to proactively verify their account details from June 6th to June 20th.

Global Macro Analysis

Cory Russell

Apr 07, 2022 11:35


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The S&P 500 index fell 1.0 percent on Wednesday. US 2s10s steepened even further, with 10yr rates rising 5 basis points to 2.6 percent, the most in three years, and 2yr yields falling 5 basis points to 2.47 percent. The price of oil has dropped by 4.7 percent.


I won't go into detail about the FED minutes since Vice-Chairman Brainard has previously laid the groundwork.


The global bond market resumed its sell-off after a March respite, causing a worsening in cross-asset risk sentiment, with global tech equities suffering the brunt of the fallout.


In a high-inflation climate, reducing the balance sheet is a substantial source of market uncertainty. However, despite the build-up of economic and geopolitical headwinds over the previous several weeks, stock markets were overbought to a great extent, so this is simply a corrective move to a more sensible level.


The major source of worry seems to be rates, so if rates manage to stabilize, we may see a systematic bid return. However, if interest rate volatility remains high, stocks may continue to be under pressure.


The overnight movement in US transport equities is the latest in a long line of smoke signals the market is sending about recession fears. No market analyst is predicting a recession with too much speed in the economy, but that does not rule out the possibility that some of the signs of one are beginning to appear.


The overall picture has shifted from a certain mid-cycle situation a month or two ago to a late-cycle likelihood presently. I've been preaching about the compressed nature of market cycles since Covid's inception, and the most recent adjustment took weeks rather than a year. Another illustration of the ticker tape's ruthlessness and the speed with which key pivots are priced.


The point is that, similar to the 2's10's inversion, although we may argue about the likelihood of a recession and if the Transports move is a signal for one, the viciousness of pricing actions has pushed people's hands whether they believe in them or not.


Even though one swallow does not make a spring, it seems that the market is concerned that the Fed is behind the curve, and that something like the Volcker adjustment is in the cards with that proviso in mind.