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On August 26th, Revolution Medicines pancreatic cancer drug Daraxonrasib received approval from US regulatory agencies, becoming the first drug to target one of the key molecular mechanisms of pancreatic cancer. The drug, marketed under the name Rasonque, is considered one of the most significant breakthroughs in pancreatic cancer treatment in recent years. According to data from the US Food and Drug Administration (FDA), a late-stage clinical trial announced in May showed that Daraxonrasib nearly doubled the typical survival of patients with a highly aggressive form of pancreatic cancer, reaching 13.2 months, while the average survival for patients receiving chemotherapy (the current standard of care) was only 6.7 months.Shipping company Mediterranean Shipping Company (MSC) has suspended its Black Sea route service to Russia due to a drone attack.On August 26, according to the Ukrainian news agency Interfax, Ukrainian President Volodymyr Zelenskyy inspected frontline troops in southern Ukraine. Zelenskyy posted on the social media platform Telegram that he and Commander-in-Chief of the Armed Forces, Dragat, visited the 80th Independent Airborne Assault Galician Brigade and the 95th Independent Airborne Assault Boriska Brigade, which were operating in the Alexandrovka direction, and met with the soldiers. Zelenskyy said that he also held talks with commanders in the Zaporizhia region and commanders at all levels of the airborne assault forces, with key topics including recruitment and providing the troops with necessary weapons and equipment.On August 26, MINIMAX-W (00100.HK) announced that, according to the Master API Service Agreement, the company agreed to provide API services to businesses operated by Alibaba Group for a period from the listing date to December 31, 2028. Under the Alibaba Cloud Computing Service Agreement, the company agreed to purchase certain cloud products and services from Alibaba Cloud Computing Limited for a period from the listing date to December 31, 2028. On August 26 (after trading hours), the company entered into supplemental agreements to the Master API Service Agreement and Alibaba Cloud Computing Service Agreement with Alibaba Cloud Computing Limited to amend the existing annual caps on continuing connected transactions under the Master API Service Agreement and Alibaba Cloud Computing Service Agreement for the years ended December 31, 2026, 2027 and 2028.The main liquefied petroleum gas (LPG) contract rose by 100.00 yuan during the day, currently trading at 5791.00 yuan/ton, an increase of 1.76%.

Gold Price Forecast: The XAU/USD pair's decline is moderating as the price recovers from recent lows

Daniel Rogers

Aug 22, 2022 14:41

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As analysts at TD Securities explained, Chair Powell's remarks will likely be "a key avenue for the Fed to push back against the notable easing in financial conditions sparked by his last remarks, which has seen markets price in rate cuts immediately following the rate hiking cycle and is likely inconsistent with the Fed's inflation mandate." As market expectations for rate reduction diminish, speculative demand for precious metals should diminish more.

 

A chorus of Fed speakers has addressed us in the lead-up to the event. In an interview with CNN, Mary Daly, president of the Federal Reserve Bank of San Francisco, stated that it was far too early to declare victory on inflation and that a 50 basis point or 75 basis point increase would be reasonable.

 

Daly's bluster stirred up the dust and pushed the US dollar up 0.12% on the day to 106.78; since then, it has skyrocketed to 108.285 in Tokyo's opening hour. US bond yields continue to rise, following Europe's selloff, and the yield curve steepened. Yields on 2-year government bonds increased from 3.23% to 3.24% thru 3.29%, while yields on 10-year government bonds increased from 2.90% to 2.97%. The rising interest rates are particularly bad news for gold investors, as the yellow metal is extremely sensitive to rising US interest rates, which increase the opportunity cost of holding non-yielding bullion.

 

Fed funds futures traders assign a likelihood of 55% that the Fed will raise rates by 50 basis points in September and a probability of 45% that rates will be raised by 75 basis points. According to calculations by Reuters and data from the US Commodity Futures Trading Commission published on Friday, speculators' net long positioning on the US dollar continues to expand, while net short positions on the euro increase. The value of the net long dollar position increased to $13.37 billion during the week ending August 16, according to statistics from the CFTC. Since four weeks ago, net long dollar positions have climbed for the first time.

 

Core PCE will be significant in data preceding the Jackson Hole Symposium. According to analysts at TD Securities, prices likely slowed significantly in July and at an even slower rate than the core CPI (0.1% vs. 0.3%).

 

"Shelter weights continue to be a major contributor to this disparity. The YoY rate likely decreased to 4.6% from 4.8% in June, indicating that the series has reached its apex. Separately, personal expenditure likely fell to a still robust 0.6% MoM pace after seeing an even greater 1.0% MoM increase in June.